All posts by rbuchan

Guangbo and Clayton publish in PLOS One

Guangbo and Clayton, together with expert help from Matt Kaplan, have published a technical protocol paper in PLOS One. The paper describes a high-throughput robotic method that allows yeast researchers to transform and genetically modify > 1000 yeast strains in a day. Congrats Guangbo and Clayton!

Nichole’s paper published in RNA!

Our first “proper” paper is out in RNA – “Defects in THO/TREX-2 function cause accumulation of novel cytoplasmic mRNP granules that can be cleared by autophagy”.  Well done Nichole, Guangbo and Kaitlyn!

http://rnajournal.cshlp.org/content/early/2016/06/01/rna.057224.116.long

Starter grant award from ALSA

We are happy to announce that the Buchan lab has been awarded a starter grant from the Amyotrophic Lateral Sclerosis Association.  This 1 year grant ($40k) will be focused on the effects of Granulophagy on clearance of ALS inclusion bodies, which share many properties in common with stress granules.

Clayton and Tam leave lab with Bachelor degrees

Both Tam and Clayton have sadly now left the lab, though not before successfully writing and submitting a research thesis, as part of their Bachelor degrees.  Clayton focused on a characterization of Vanillin-induced stress granules in yeast, and high-throughput methods for screening stress granule/P-body phenotypes.  Tam focused on the role of Cdc48/VCP on stress granule clearance, both in yeast and mammalian cell models.  Thanks for your hard work guys, you will be missed.

Guangbo Liu joins lab

We have hired our first postdoc!  Guangbo Liu has joined us, following a productive PhD at Shangdong University and UCSD (in the lab of Kun-liang Guan).  During his PhD, Guangbo studied aspects of apoptosis, cancer and the Hippo signaling pathway.  Welcome Guangbo!

Tam presents poster at “Vision to Your Future” conference

Tam presented a poster entitled “Stress granules and Cdc48/p97 help cells adapt to stress” at the Vision to Your Future conference.

The conference was held at the BIO5 Keating and MRB buildings on October 18th, and gives undergraduate students in particular a chance to present their work to an audience of teachers and high school students.

Well done Tam!